Three actions to composing a very early phase adaptive research protocol

Step 1: define and explain adaptive features


Adaptive features will be the traits of pre-defined adaptations which can be built to the protocol and research conduct.


When defining adaptive features one has to establish firstly which protocol areas will or may need flexibility allowing for adaptation, in other words. the groups of adaptations. Next, you need to establish the information of prospective adaptations, i.e. specific features that are adaptive. The usage of some features that are adaptive be sure through the outset (such as for instance dosage selection in a report where doses haven’t been set within the protocol), other people are going to be optional (such as for instance addition of pretty much research individuals, information analysis etc.).